The IAAF says biology has to trump gender identity after welcoming the decision to permit restrictions in testosterone levels of female runners.
Double Olympic champion Caster Semenya twice appealed against the new IAAF rule that prevents her from running in the 800 metres without medication.
A Swiss court had suspended the ruling, but that has now been lifted.
Semenya says she will not defend her 800-metres World title this year.
The IAAF -Double-A-F says competitors now have parity and clarity before the championships in Doha, which begin on September 28.