Home favourite Caroline Garcia became the highest-ranked women’s player to exit the French Open so far with a second-round loss to Anna Blinkova.
Fifth seed Garcia saved eight match points before succumbing to a 4-6, 6-3, 7-5 defeat by the Russian.
It came after former champion Jelena Ostapenko suffered a shock defeat by tournament debutant Peyton Stearns.
But second seed Aryna Sabalenka avoided a scare with a straight-set win over qualifier Iryna Shymanovich.
Australian Open champion Sabalenka beat fellow Belarusian Shymanovich 7-5, 6-2.
Meanwhile, France’s sports minister, Amelie Oudea-Castera, says Novak Djokovic’s political message about Kosovo at the French Open was “not appropriate” and “shouldn’t happen again.”
Oudea-Castera said there needs to be a “principle of neutrality for the field of play”.
Serb Djokovic wrote “Kosovo is the heart of Serbia. Stop the violence” on a camera lens.
It is in reference to recent tension in Kosovo, which declared independence from Serbia in 2008.
Serbia has never recognised Kosovo’s independence and there has been violence in the past days following the installation of ethnic Albanian mayors in the north of the country, with police and Nato troops clashing with Serb protesters.
World governing body the International Tennis Federation said Djokovic’s statement did not violate any rules because the Grand Slam rulebook does not ban political statements.